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予測モデル(Ion Channel)

相互作用(リガンド)データ数 ◎:500~、○:100~499、△:1~99、x:0

UniProt ID Accession Number Protein Name Model
Standard ChEMBL
5HT3A_HUMAN P46098 5-hydroxytryptamine receptor 3A
5HT3B_HUMAN O95264 5-hydroxytryptamine receptor 3B
5HT3C_HUMAN Q8WXA8 5-hydroxytryptamine receptor 3C
5HT3D_HUMAN Q70Z44 5-hydroxytryptamine receptor 3D
5HT3E_HUMAN A5X5Y0 5-hydroxytryptamine receptor 3E
ABCC8_HUMAN Q09428 ATP-binding cassette sub-family C member 8
ABCC9_HUMAN O60706 ATP-binding cassette sub-family C member 9
ACH10_HUMAN Q9GZZ6 Neuronal acetylcholine receptor subunit alpha-10
ACHA_HUMAN P02708 Acetylcholine receptor subunit alpha
ACHA2_HUMAN Q15822 Neuronal acetylcholine receptor subunit alpha-2
ACHA3_HUMAN P32297 Neuronal acetylcholine receptor subunit alpha-3
ACHA4_HUMAN P43681 Neuronal acetylcholine receptor subunit alpha-4
ACHA5_HUMAN P30532 Neuronal acetylcholine receptor subunit alpha-5
ACHA6_HUMAN Q15825 Neuronal acetylcholine receptor subunit alpha-6
ACHA7_HUMAN P36544 Neuronal acetylcholine receptor subunit alpha-7
ACHA9_HUMAN Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9
ACHB_HUMAN P11230 Acetylcholine receptor subunit beta
ACHB2_HUMAN P17787 Neuronal acetylcholine receptor subunit beta-2
ACHB3_HUMAN Q05901 Neuronal acetylcholine receptor subunit beta-3
ACHB4_HUMAN P30926 Neuronal acetylcholine receptor subunit beta-4
ACHD_HUMAN Q07001 Acetylcholine receptor subunit delta
ACHE_HUMAN Q04844 Acetylcholine receptor subunit epsilon
ACHG_HUMAN P07510 Acetylcholine receptor subunit gamma
ANO1_HUMAN Q5XXA6 Anoctamin-1
ASIC1_HUMAN P78348 Acid-sensing ion channel 1
ASIC2_HUMAN Q16515 Acid-sensing ion channel 2 x
ASIC3_HUMAN Q9UHC3 Acid-sensing ion channel 3
CA2D1_HUMAN P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1
CA2D2_HUMAN Q9NY47 Voltage-dependent calcium channel subunit alpha-2/delta-2
CA2D3_HUMAN Q8IZS8 Voltage-dependent calcium channel subunit alpha-2/delta-3 x
CA2D4_HUMAN Q7Z3S7 Voltage-dependent calcium channel subunit alpha-2/delta-4 x
CAC1A_HUMAN O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A
CAC1B_HUMAN Q00975 Voltage-dependent N-type calcium channel subunit alpha-1B
CAC1C_HUMAN Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C
CAC1D_HUMAN Q01668 Voltage-dependent L-type calcium channel subunit alpha-1D
CAC1E_HUMAN Q15878 Voltage-dependent R-type calcium channel subunit alpha-1E x
CAC1F_HUMAN O60840 Voltage-dependent L-type calcium channel subunit alpha-1F
CAC1G_HUMAN O43497 Voltage-dependent T-type calcium channel subunit alpha-1G
CAC1H_HUMAN O95180 Voltage-dependent T-type calcium channel subunit alpha-1H
CAC1I_HUMAN Q9P0X4 Voltage-dependent T-type calcium channel subunit alpha-1I
CAC1S_HUMAN Q13698 Voltage-dependent L-type calcium channel subunit alpha-1S
CACB1_HUMAN Q02641 Voltage-dependent L-type calcium channel subunit beta-1 x
CACB2_HUMAN Q08289 Voltage-dependent L-type calcium channel subunit beta-2 x
CACB3_HUMAN P54284 Voltage-dependent L-type calcium channel subunit beta-3 x
CACB4_HUMAN O00305 Voltage-dependent L-type calcium channel subunit beta-4 x
CCG1_HUMAN Q06432 Voltage-dependent calcium channel gamma-1 subunit x
CFTR_HUMAN P13569 Cystic fibrosis transmembrane conductance regulator
CLCA1_HUMAN A8K7I4 Calcium-activated chloride channel regulator 1 x
CLCA2_HUMAN Q9UQC9 Calcium-activated chloride channel regulator 2 x
CLCKA_HUMAN P51800 Chloride channel protein ClC-Ka x
CLCKB_HUMAN P51801 Chloride channel protein ClC-Kb x
CLCN1_HUMAN P35523 Chloride channel protein 1 x
CLCN2_HUMAN P51788 Chloride channel protein 2 x
CLCN7_HUMAN P51798 H(+)/Cl(-) exchange transporter 7 x
CNGA1_HUMAN P29973 cGMP-gated cation channel alpha-1 x
CNGA2_HUMAN Q16280 Cyclic nucleotide-gated olfactory channel x
CRCM1_HUMAN Q96D31 Calcium release-activated calcium channel protein 1
CTSR1_HUMAN Q8NEC5 Cation channel sperm-associated protein 1 x
CY24B_HUMAN P04839 Cytochrome b-245 heavy chain
GBRA1_HUMAN P14867 Gamma-aminobutyric acid receptor subunit alpha-1
GBRA2_HUMAN P47869 Gamma-aminobutyric acid receptor subunit alpha-2
GBRA3_HUMAN P34903 Gamma-aminobutyric acid receptor subunit alpha-3
GBRA4_HUMAN P48169 Gamma-aminobutyric acid receptor subunit alpha-4
GBRA5_HUMAN P31644 Gamma-aminobutyric acid receptor subunit alpha-5
GBRA6_HUMAN Q16445 Gamma-aminobutyric acid receptor subunit alpha-6
GBRB1_HUMAN P18505 Gamma-aminobutyric acid receptor subunit beta-1
GBRB2_HUMAN P47870 Gamma-aminobutyric acid receptor subunit beta-2
GBRB3_HUMAN P28472 Gamma-aminobutyric acid receptor subunit beta-3
GBRD_HUMAN O14764 Gamma-aminobutyric acid receptor subunit delta
GBRE_HUMAN P78334 Gamma-aminobutyric acid receptor subunit epsilon
GBRG1_HUMAN Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1
GBRG2_HUMAN P18507 Gamma-aminobutyric acid receptor subunit gamma-2
GBRG3_HUMAN Q99928 Gamma-aminobutyric acid receptor subunit gamma-3
GBRP_HUMAN O00591 Gamma-aminobutyric acid receptor subunit pi
GBRR1_HUMAN P24046 Gamma-aminobutyric acid receptor subunit rho-1
GBRR2_HUMAN P28476 Gamma-aminobutyric acid receptor subunit rho-2
GBRR3_HUMAN A8MPY1 Gamma-aminobutyric acid receptor subunit rho-3
GBRT_HUMAN Q9UN88 Gamma-aminobutyric acid receptor subunit theta
GLRA1_HUMAN P23415 Glycine receptor subunit alpha-1
GLRA2_HUMAN P23416 Glycine receptor subunit alpha-2
GLRA3_HUMAN O75311 Glycine receptor subunit alpha-3
GLRA4_HUMAN Q5JXX5 Glycine receptor subunit alpha-4 x
GLRB_HUMAN P48167 Glycine receptor subunit beta x
GRIA1_HUMAN P42261 Glutamate receptor 1
GRIA2_HUMAN P42262 Glutamate receptor 2
GRIA3_HUMAN P42263 Glutamate receptor 3
GRIA4_HUMAN P48058 Glutamate receptor 4
GRID1_HUMAN Q9ULK0 "Glutamate receptor ionotropic, delta-1" x
GRID2_HUMAN O43424 "Glutamate receptor ionotropic, delta-2" x
GRIK1_HUMAN P39086 "Glutamate receptor ionotropic, kainate 1"
GRIK2_HUMAN Q13002 "Glutamate receptor ionotropic, kainate 2"
GRIK3_HUMAN Q13003 "Glutamate receptor ionotropic, kainate 3"
GRIK4_HUMAN Q16099 "Glutamate receptor ionotropic, kainate 4"
GRIK5_HUMAN Q16478 "Glutamate receptor ionotropic, kainate 5"
HCN1_HUMAN O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
HCN2_HUMAN Q9UL51 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
HCN3_HUMAN Q9P1Z3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
HCN4_HUMAN Q9Y3Q4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
ICLN_HUMAN P54105 Methylosome subunit pICln x
ITPR1_HUMAN Q14643 "Inositol 1,4,5-trisphosphate receptor type 1"
ITPR2_HUMAN Q14571 "Inositol 1,4,5-trisphosphate receptor type 2"
ITPR3_HUMAN Q14573 "Inositol 1,4,5-trisphosphate receptor type 3"
KCAB1_HUMAN Q14722 Voltage-gated potassium channel subunit beta-1 x
KCIP2_HUMAN Q9NS61 Kv channel-interacting protein 2 x
KCJ10_HUMAN P78508 ATP-sensitive inward rectifier potassium channel 10 x
KCJ11_HUMAN Q14654 ATP-sensitive inward rectifier potassium channel 11
KCJ12_HUMAN Q14500 ATP-sensitive inward rectifier potassium channel 12 x
KCMA1_HUMAN Q12791 Calcium-activated potassium channel subunit alpha-1
KCMB1_HUMAN Q16558 Calcium-activated potassium channel subunit beta-1 x
KCMB2_HUMAN Q9Y691 Calcium-activated potassium channel subunit beta-2 x
KCMB3_HUMAN Q9NPA1 Calcium-activated potassium channel subunit beta-3 x
KCMB4_HUMAN Q86W47 Calcium-activated potassium channel subunit beta-4 x
KCNA1_HUMAN Q09470 Potassium voltage-gated channel subfamily A member 1
KCNA2_HUMAN P16389 Potassium voltage-gated channel subfamily A member 2
KCNA3_HUMAN P22001 Potassium voltage-gated channel subfamily A member 3
KCNA4_HUMAN P22459 Potassium voltage-gated channel subfamily A member 4
KCNA5_HUMAN P22460 Potassium voltage-gated channel subfamily A member 5
KCNA6_HUMAN P17658 Potassium voltage-gated channel subfamily A member 6 x
KCNA7_HUMAN Q96RP8 Potassium voltage-gated channel subfamily A member 7 x
KCNB1_HUMAN Q14721 Potassium voltage-gated channel subfamily B member 1
KCNB2_HUMAN Q92953 Potassium voltage-gated channel subfamily B member 2
KCNC1_HUMAN P48547 Potassium voltage-gated channel subfamily C member 1
KCNC2_HUMAN Q96PR1 Potassium voltage-gated channel subfamily C member 2 x
KCNC4_HUMAN Q03721 Potassium voltage-gated channel subfamily C member 4 x
KCND2_HUMAN Q9NZV8 Potassium voltage-gated channel subfamily D member 2 x
KCND3_HUMAN Q9UK17 Potassium voltage-gated channel subfamily D member 3
KCNE1_HUMAN P15382 Potassium voltage-gated channel subfamily E member 1
KCNE2_HUMAN Q9Y6J6 Potassium voltage-gated channel subfamily E member 2 x
KCNE3_HUMAN Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 x
KCNH1_HUMAN O95259 Potassium voltage-gated channel subfamily H member 1 x
KCNH2_HUMAN Q12809 Potassium voltage-gated channel subfamily H member 2
KCNH3_HUMAN Q9ULD8 Potassium voltage-gated channel subfamily H member 3 x
KCNH4_HUMAN Q9UQ05 Potassium voltage-gated channel subfamily H member 4 x
KCNH5_HUMAN Q8NCM2 Potassium voltage-gated channel subfamily H member 5 x
KCNH6_HUMAN Q9H252 Potassium voltage-gated channel subfamily H member 6 x
KCNJ1_HUMAN P48048 ATP-sensitive inward rectifier potassium channel 1
KCNJ2_HUMAN P63252 Inward rectifier potassium channel 2 x
KCNJ3_HUMAN P48549 G protein-activated inward rectifier potassium channel 1
KCNJ4_HUMAN P48050 Inward rectifier potassium channel 4
KCNJ5_HUMAN P48544 G protein-activated inward rectifier potassium channel 4
KCNJ6_HUMAN P48051 G protein-activated inward rectifier potassium channel 2
KCNJ8_HUMAN Q15842 ATP-sensitive inward rectifier potassium channel 8
KCNK1_HUMAN O00180 Potassium channel subfamily K member 1 x
KCNK2_HUMAN O95069 Potassium channel subfamily K member 2
KCNK3_HUMAN O14649 Potassium channel subfamily K member 3
KCNK4_HUMAN Q9NYG8 Potassium channel subfamily K member 4 x
KCNK6_HUMAN Q9Y257 Potassium channel subfamily K member 6 x
KCNK9_HUMAN Q9NPC2 Potassium channel subfamily K member 9
KCNKA_HUMAN P57789 Potassium channel subfamily K member 10 x
KCNKI_HUMAN Q7Z418 Potassium channel subfamily K member 18 x
KCNN1_HUMAN Q92952 Small conductance calcium-activated potassium channel protein 1
KCNN2_HUMAN Q9H2S1 Small conductance calcium-activated potassium channel protein 2
KCNN3_HUMAN Q9UGI6 Small conductance calcium-activated potassium channel protein 3
KCNN4_HUMAN O15554 Intermediate conductance calcium-activated potassium channel protein 4
KCNQ1_HUMAN P51787 Potassium voltage-gated channel subfamily KQT member 1
KCNQ2_HUMAN O43526 Potassium voltage-gated channel subfamily KQT member 2
KCNQ3_HUMAN O43525 Potassium voltage-gated channel subfamily KQT member 3
KCNQ4_HUMAN P56696 Potassium voltage-gated channel subfamily KQT member 4
KCNQ5_HUMAN Q9NR82 Potassium voltage-gated channel subfamily KQT member 5
MCLN3_HUMAN Q8TDD5 Mucolipin-3
NMD3A_HUMAN Q8TCU5 "Glutamate receptor ionotropic, NMDA 3A"
NMD3B_HUMAN O60391 "Glutamate receptor ionotropic, NMDA 3B"
NMDE1_HUMAN Q12879 "Glutamate receptor ionotropic, NMDA 2A"
NMDE2_HUMAN Q13224 "Glutamate receptor ionotropic, NMDA 2B"
NMDE3_HUMAN Q14957 "Glutamate receptor ionotropic, NMDA 2C"
NMDE4_HUMAN O15399 "Glutamate receptor ionotropic, NMDA 2D"
NMDZ1_HUMAN Q05586 "Glutamate receptor ionotropic, NMDA 1"
NOX1_HUMAN Q9Y5S8 NADPH oxidase 1
NOX5_HUMAN Q96PH1 NADPH oxidase 5
ORAI2_HUMAN Q96SN7 Protein orai-2 x
P2RX1_HUMAN P51575 P2X purinoceptor 1
P2RX2_HUMAN Q9UBL9 P2X purinoceptor 2
P2RX3_HUMAN P56373 P2X purinoceptor 3
P2RX4_HUMAN Q99571 P2X purinoceptor 4
P2RX5_HUMAN Q93086 P2X purinoceptor 5 x
P2RX6_HUMAN O15547 P2X purinoceptor 6 x
P2RX7_HUMAN Q99572 P2X purinoceptor 7
PANX1_HUMAN Q96RD7 Pannexin-1 x
PK2L1_HUMAN Q9P0L9 Polycystic kidney disease 2-like 1 protein x
PKD2_HUMAN Q13563 Polycystin-2
RYR1_HUMAN P21817 Ryanodine receptor 1
RYR2_HUMAN Q92736 Ryanodine receptor 2 x
RYR3_HUMAN Q15413 Ryanodine receptor 3 x
SCN1A_HUMAN P35498 Sodium channel protein type 1 subunit alpha
SCN1B_HUMAN Q07699 Sodium channel subunit beta-1 x
SCN2A_HUMAN Q99250 Sodium channel protein type 2 subunit alpha
SCN2B_HUMAN O60939 Sodium channel subunit beta-2 x
SCN3A_HUMAN Q9NY46 Sodium channel protein type 3 subunit alpha
SCN3B_HUMAN Q9NY72 Sodium channel subunit beta-3 x
SCN4A_HUMAN P35499 Sodium channel protein type 4 subunit alpha
SCN4B_HUMAN Q8IWT1 Sodium channel subunit beta-4 x
SCN5A_HUMAN Q14524 Sodium channel protein type 5 subunit alpha
SCN7A_HUMAN Q01118 Sodium channel protein type 7 subunit alpha
SCN8A_HUMAN Q9UQD0 Sodium channel protein type 8 subunit alpha
SCN9A_HUMAN Q15858 Sodium channel protein type 9 subunit alpha
SCNAA_HUMAN Q9Y5Y9 Sodium channel protein type 10 subunit alpha
SCNBA_HUMAN Q9UI33 Sodium channel protein type 11 subunit alpha
SCNNA_HUMAN P37088 Amiloride-sensitive sodium channel subunit alpha
SCNNB_HUMAN P51168 Amiloride-sensitive sodium channel subunit beta x
SCNND_HUMAN P51172 Amiloride-sensitive sodium channel subunit delta x
SCNNG_HUMAN P51170 Amiloride-sensitive sodium channel subunit gamma x
TRPA1_HUMAN O75762 Transient receptor potential cation channel subfamily A member 1
TRPC3_HUMAN Q13507 Short transient receptor potential channel 3
TRPC5_HUMAN Q9UL62 Short transient receptor potential channel 5 x
TRPC6_HUMAN Q9Y210 Short transient receptor potential channel 6
TRPM2_HUMAN O94759 Transient receptor potential cation channel subfamily M member 2
TRPM3_HUMAN Q9HCF6 Transient receptor potential cation channel subfamily M member 3 x
TRPM4_HUMAN Q8TD43 Transient receptor potential cation channel subfamily M member 4 x
TRPM5_HUMAN Q9NZQ8 Transient receptor potential cation channel subfamily M member 5 x
TRPM6_HUMAN Q9BX84 Transient receptor potential cation channel subfamily M member 6
TRPM7_HUMAN Q96QT4 Transient receptor potential cation channel subfamily M member 7 x
TRPM8_HUMAN Q7Z2W7 Transient receptor potential cation channel subfamily M member 8
TRPV1_HUMAN Q8NER1 Transient receptor potential cation channel subfamily V member 1
TRPV2_HUMAN Q9Y5S1 Transient receptor potential cation channel subfamily V member 2 x
TRPV3_HUMAN Q8NET8 Transient receptor potential cation channel subfamily V member 3
TRPV4_HUMAN Q9HBA0 Transient receptor potential cation channel subfamily V member 4
TRPV6_HUMAN Q9H1D0 Transient receptor potential cation channel subfamily V member 6 x
ZACN_HUMAN Q401N2 Zinc-activated ligand-gated ion channel x
Total target proteins: 218 146

2017年5月公開