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予測モデル(GPCR)

相互作用(リガンド)データ数 ◎:500~、○:100~499、△:1~99、x:0

UniProt ID Accession Number Protein Name Model
Standard ChEMBL
5HT1A_HUMAN P08908 5-hydroxytryptamine receptor 1A
5HT1B_HUMAN P28222 5-hydroxytryptamine receptor 1B
5HT1D_HUMAN P28221 5-hydroxytryptamine receptor 1D
5HT1E_HUMAN P28566 5-hydroxytryptamine receptor 1E
5HT1F_HUMAN P30939 5-hydroxytryptamine receptor 1F
5HT2A_HUMAN P28223 5-hydroxytryptamine receptor 2A
5HT2B_HUMAN P41595 5-hydroxytryptamine receptor 2B
5HT2C_HUMAN P28335 5-hydroxytryptamine receptor 2C
5HT4R_HUMAN Q13639 5-hydroxytryptamine receptor 4
5HT5A_HUMAN P47898 5-hydroxytryptamine receptor 5A
5HT6R_HUMAN P50406 5-hydroxytryptamine receptor 6
5HT7R_HUMAN P34969 5-hydroxytryptamine receptor 7
AA1R_HUMAN P30542 Adenosine receptor A1
AA2AR_HUMAN P29274 Adenosine receptor A2a
AA2BR_HUMAN P29275 Adenosine receptor A2b
AA3R_HUMAN P33765 Adenosine receptor A3 x
ACKR3_HUMAN P25106 Atypical chemokine receptor 3
ACKR4_HUMAN Q9NPB9 Atypical chemokine receptor 4 x
ACM1_HUMAN P11229 Muscarinic acetylcholine receptor M1
ACM2_HUMAN P08172 Muscarinic acetylcholine receptor M2
ACM3_HUMAN P20309 Muscarinic acetylcholine receptor M3
ACM4_HUMAN P08173 Muscarinic acetylcholine receptor M4
ACM5_HUMAN P08912 Muscarinic acetylcholine receptor M5
ACTHR_HUMAN Q01718 Adrenocorticotropic hormone receptor
ADA1A_HUMAN P35348 Alpha-1A adrenergic receptor
ADA1B_HUMAN P35368 Alpha-1B adrenergic receptor
ADA1D_HUMAN P25100 Alpha-1D adrenergic receptor
ADA2A_HUMAN P08913 Alpha-2A adrenergic receptor
ADA2B_HUMAN P18089 Alpha-2B adrenergic receptor
ADA2C_HUMAN P18825 Alpha-2C adrenergic receptor
ADRB1_HUMAN P08588 Beta-1 adrenergic receptor
ADRB2_HUMAN P07550 Beta-2 adrenergic receptor
ADRB3_HUMAN P13945 Beta-3 adrenergic receptor
AGTR1_HUMAN P30556 Type-1 angiotensin II receptor
AGTR2_HUMAN P50052 Type-2 angiotensin II receptor
APJ_HUMAN P35414 Apelin receptor
BKRB1_HUMAN P46663 B1 bradykinin receptor
BKRB2_HUMAN P30411 B2 bradykinin receptor
BRS3_HUMAN P32247 Bombesin receptor subtype-3
C3AR_HUMAN Q16581 C3a anaphylatoxin chemotactic receptor
C5AR1_HUMAN P21730 C5a anaphylatoxin chemotactic receptor 1
CALCR_HUMAN P30988 Calcitonin receptor
CALRL_HUMAN Q16602 Calcitonin gene-related peptide type 1 receptor
CASR_HUMAN P41180 Extracellular calcium-sensing receptor
CCKAR_HUMAN P32238 Cholecystokinin receptor type A
CCR1_HUMAN P32246 C-C chemokine receptor type 1
CCR10_HUMAN P46092 C-C chemokine receptor type 10 x
CCR2_HUMAN P41597 C-C chemokine receptor type 2
CCR3_HUMAN P51677 C-C chemokine receptor type 3
CCR4_HUMAN P51679 C-C chemokine receptor type 4
CCR5_HUMAN P51681 C-C chemokine receptor type 5
CCR6_HUMAN P51684 C-C chemokine receptor type 6
CCR7_HUMAN P32248 C-C chemokine receptor type 7 x
CCR8_HUMAN P51685 C-C chemokine receptor type 8
CCR9_HUMAN P51686 C-C chemokine receptor type 9
CCRL2_HUMAN O00421 C-C chemokine receptor-like 2 x
CLTR1_HUMAN Q9Y271 Cysteinyl leukotriene receptor 1
CLTR2_HUMAN Q9NS75 Cysteinyl leukotriene receptor 2
CML1_HUMAN Q99788 Chemokine-like receptor 1 x
CNR1_HUMAN P21554 Cannabinoid receptor 1
CNR2_HUMAN P34972 Cannabinoid receptor 2
CRFR1_HUMAN P34998 Corticotropin-releasing factor receptor 1
CRFR2_HUMAN Q13324 Corticotropin-releasing factor receptor 2
CX3C1_HUMAN P49238 CX3C chemokine receptor 1
CXCR1_HUMAN P25024 C-X-C chemokine receptor type 1
CXCR2_HUMAN P25025 C-X-C chemokine receptor type 2
CXCR3_HUMAN P49682 C-X-C chemokine receptor type 3
CXCR4_HUMAN P61073 C-X-C chemokine receptor type 4
CXCR5_HUMAN P32302 C-X-C chemokine receptor type 5
DRD1_HUMAN P21728 D(1A) dopamine receptor
DRD2_HUMAN P14416 D(2) dopamine receptor
DRD3_HUMAN P35462 D(3) dopamine receptor
DRD4_HUMAN P21917 D(4) dopamine receptor
DRD5_HUMAN P21918 D(1B) dopamine receptor
EDNRA_HUMAN P25101 Endothelin-1 receptor
EDNRB_HUMAN P24530 Endothelin B receptor
FFAR1_HUMAN O14842 Free fatty acid receptor 1
FFAR2_HUMAN O15552 Free fatty acid receptor 2
FFAR3_HUMAN O14843 Free fatty acid receptor 3 x
FFAR4_HUMAN Q5NUL3 Free fatty acid receptor 4
FPR1_HUMAN P21462 fMet-Leu-Phe receptor
FPR2_HUMAN P25090 N-formyl peptide receptor 2
FPR3_HUMAN P25089 N-formyl peptide receptor 3
FSHR_HUMAN P23945 Follicle-stimulating hormone receptor
GABR1_HUMAN Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1
GABR2_HUMAN O75899 Gamma-aminobutyric acid type B receptor subunit 2
GALR1_HUMAN P47211 Galanin receptor type 1
GALR2_HUMAN O43603 Galanin receptor type 2
GALR3_HUMAN O60755 Galanin receptor type 3
GASR_HUMAN P32239 Gastrin/cholecystokinin type B receptor
GHRHR_HUMAN Q02643 Growth hormone-releasing hormone receptor
GHSR_HUMAN Q92847 Growth hormone secretagogue receptor type 1
GIPR_HUMAN P48546 Gastric inhibitory polypeptide receptor
GLP1R_HUMAN P43220 Glucagon-like peptide 1 receptor
GLP2R_HUMAN O95838 Glucagon-like peptide 2 receptor x
GLR_HUMAN P47871 Glucagon receptor
GNRHR_HUMAN P30968 Gonadotropin-releasing hormone receptor
GP116_HUMAN Q8IZF2 Probable G-protein coupled receptor 116 x
GP119_HUMAN Q8TDV5 Glucose-dependent insulinotropic receptor
GP142_HUMAN Q7Z601 Probable G-protein coupled receptor 142
GP174_HUMAN Q9BXC1 Probable G-protein coupled receptor 174 x
GP182_HUMAN O15218 G-protein coupled receptor 182 x
GP183_HUMAN P32249 G-protein coupled receptor 183
GPBAR_HUMAN Q8TDU6 G-protein coupled bile acid receptor 1
GPC6A_HUMAN Q5T6X5 G-protein coupled receptor family C group 6 member A x
GPER1_HUMAN Q99527 G-protein coupled estrogen receptor 1
GPR1_HUMAN P46091 G-protein coupled receptor 1 x
GPR17_HUMAN Q13304 Uracil nucleotide/cysteinyl leukotriene receptor
GPR18_HUMAN Q14330 N-arachidonyl glycine receptor
GPR34_HUMAN Q9UPC5 Probable G-protein coupled receptor 34
GPR35_HUMAN Q9HC97 G-protein coupled receptor 35
GPR39_HUMAN O43194 G-protein coupled receptor 39
GPR4_HUMAN P46093 G-protein coupled receptor 4
GPR52_HUMAN Q9Y2T5 Probable G-protein coupled receptor 52
GPR55_HUMAN Q9Y2T6 G-protein coupled receptor 55
GPR83_HUMAN Q9NYM4 Probable G-protein coupled receptor 83 x
GPR84_HUMAN Q9NQS5 G-protein coupled receptor 84 x
GPR88_HUMAN Q9GZN0 Probable G-protein coupled receptor 88
GRM1_HUMAN Q13255 Metabotropic glutamate receptor 1
GRM2_HUMAN Q14416 Metabotropic glutamate receptor 2
GRM3_HUMAN Q14832 Metabotropic glutamate receptor 3
GRM4_HUMAN Q14833 Metabotropic glutamate receptor 4
GRM5_HUMAN P41594 Metabotropic glutamate receptor 5
GRM6_HUMAN O15303 Metabotropic glutamate receptor 6
GRM7_HUMAN Q14831 Metabotropic glutamate receptor 7
GRM8_HUMAN O00222 Metabotropic glutamate receptor 8
GRPR_HUMAN P30550 Gastrin-releasing peptide receptor
HCAR1_HUMAN Q9BXC0 Hydroxycarboxylic acid receptor 1
HCAR2_HUMAN Q8TDS4 Hydroxycarboxylic acid receptor 2
HCAR3_HUMAN P49019 Hydroxycarboxylic acid receptor 3
HRH1_HUMAN P35367 Histamine H1 receptor
HRH2_HUMAN P25021 Histamine H2 receptor
HRH3_HUMAN Q9Y5N1 Histamine H3 receptor
HRH4_HUMAN Q9H3N8 Histamine H4 receptor
KISSR_HUMAN Q969F8 KiSS-1 receptor
LPAR1_HUMAN Q92633 Lysophosphatidic acid receptor 1
LPAR2_HUMAN Q9HBW0 Lysophosphatidic acid receptor 2
LPAR3_HUMAN Q9UBY5 Lysophosphatidic acid receptor 3
LPAR4_HUMAN Q99677 Lysophosphatidic acid receptor 4
LPAR5_HUMAN Q9H1C0 Lysophosphatidic acid receptor 5
LPAR6_HUMAN P43657 Lysophosphatidic acid receptor 6
LSHR_HUMAN P22888 Lutropin-choriogonadotropic hormone receptor
LT4R1_HUMAN Q15722 Leukotriene B4 receptor 1
LT4R2_HUMAN Q9NPC1 Leukotriene B4 receptor 2
MC3R_HUMAN P41968 Melanocortin receptor 3
MC4R_HUMAN P32245 Melanocortin receptor 4
MC5R_HUMAN P33032 Melanocortin receptor 5
MCHR1_HUMAN Q99705 Melanin-concentrating hormone receptor 1
MCHR2_HUMAN Q969V1 Melanin-concentrating hormone receptor 2
MRGX1_HUMAN Q96LB2 Mas-related G-protein coupled receptor member X1
MRGX2_HUMAN Q96LB1 Mas-related G-protein coupled receptor member X2
MSHR_HUMAN Q01726 Melanocyte-stimulating hormone receptor
MTLR_HUMAN O43193 Motilin receptor
MTR1A_HUMAN P48039 Melatonin receptor type 1A
MTR1B_HUMAN P49286 Melatonin receptor type 1B
MTR1L_HUMAN Q13585 Melatonin-related receptor x
NK1R_HUMAN P25103 Substance-P receptor
NK2R_HUMAN P21452 Substance-K receptor
NK3R_HUMAN P29371 Neuromedin-K receptor
NMBR_HUMAN P28336 Neuromedin-B receptor
NMUR1_HUMAN Q9HB89 Neuromedin-U receptor 1
NMUR2_HUMAN Q9GZQ4 Neuromedin-U receptor 2
NPBW1_HUMAN P48145 Neuropeptides B/W receptor type 1
NPBW2_HUMAN P48146 Neuropeptides B/W receptor type 2 x
NPFF1_HUMAN Q9GZQ6 Neuropeptide FF receptor 1
NPFF2_HUMAN Q9Y5X5 Neuropeptide FF receptor 2
NPSR1_HUMAN Q6W5P4 Neuropeptide S receptor
NPY1R_HUMAN P25929 Neuropeptide Y receptor type 1
NPY2R_HUMAN P49146 Neuropeptide Y receptor type 2
NPY4R_HUMAN P50391 Neuropeptide Y receptor type 4
NPY5R_HUMAN Q15761 Neuropeptide Y receptor type 5
NPY6R_HUMAN Q99463 Putative neuropeptide Y receptor type 6 x
NTR1_HUMAN P30989 Neurotensin receptor type 1
NTR2_HUMAN O95665 Neurotensin receptor type 2
OPN4_HUMAN Q9UHM6 Melanopsin x
OPRD_HUMAN P41143 Delta-type opioid receptor
OPRK_HUMAN P41145 Kappa-type opioid receptor
OPRM_HUMAN P35372 Mu-type opioid receptor
OPRX_HUMAN P41146 Nociceptin receptor
OPSD_HUMAN P08100 Rhodopsin x
OR1D2_HUMAN P34982 Olfactory receptor 1D2 x
OX1R_HUMAN O43613 Orexin receptor type 1
OX2R_HUMAN O43614 Orexin receptor type 2
OXER1_HUMAN Q8TDS5 Oxoeicosanoid receptor 1
OXGR1_HUMAN Q96P68 2-oxoglutarate receptor 1
OXYR_HUMAN P30559 Oxytocin receptor
P2RY1_HUMAN P47900 P2Y purinoceptor 1
P2RY2_HUMAN P41231 P2Y purinoceptor 2
P2RY4_HUMAN P51582 P2Y purinoceptor 4
P2RY6_HUMAN Q15077 P2Y purinoceptor 6
P2RY8_HUMAN Q86VZ1 P2Y purinoceptor 8 x
P2Y10_HUMAN O00398 Putative P2Y purinoceptor 10
P2Y11_HUMAN Q96G91 P2Y purinoceptor 11
P2Y12_HUMAN Q9H244 P2Y purinoceptor 12
P2Y13_HUMAN Q9BPV8 P2Y purinoceptor 13 x
P2Y14_HUMAN Q15391 P2Y purinoceptor 14
PACR_HUMAN P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor
PAR1_HUMAN P25116 Proteinase-activated receptor 1
PAR2_HUMAN P55085 Proteinase-activated receptor 2
PAR3_HUMAN O00254 Proteinase-activated receptor 3 x
PAR4_HUMAN Q96RI0 Proteinase-activated receptor 4
PD2R_HUMAN Q13258 Prostaglandin D2 receptor 2
PD2R2_HUMAN Q9Y5Y4 Prostaglandin D2 receptor
PE2R1_HUMAN P34995 Prostaglandin E2 receptor EP1 subtype
PE2R2_HUMAN P43116 Prostaglandin E2 receptor EP2 subtype
PE2R3_HUMAN P43115 Prostaglandin E2 receptor EP3 subtype
PE2R4_HUMAN P35408 Prostaglandin E2 receptor EP4 subtype
PF2R_HUMAN P43088 Prostaglandin F2-alpha receptor
PI2R_HUMAN P43119 Prostacyclin receptor
PKR1_HUMAN Q8TCW9 Prokineticin receptor 1
PKR2_HUMAN Q8NFJ6 Prokineticin receptor 2
PSYR_HUMAN Q8IYL9 Psychosine receptor x
PTAFR_HUMAN P25105 Platelet-activating factor receptor
PTH1R_HUMAN Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor
PTH2R_HUMAN P49190 Parathyroid hormone 2 receptor
QRFPR_HUMAN Q96P65 Pyroglutamylated RFamide peptide receptor x
RL3R1_HUMAN Q9NSD7 Relaxin-3 receptor 1 x x
RL3R2_HUMAN Q8TDU9 Relaxin-3 receptor 2 x
RXFP1_HUMAN Q9HBX9 Relaxin receptor 1
S1PR1_HUMAN P21453 Sphingosine 1-phosphate receptor 1
S1PR2_HUMAN O95136 Sphingosine 1-phosphate receptor 2
S1PR3_HUMAN Q99500 Sphingosine 1-phosphate receptor 3
S1PR4_HUMAN O95977 Sphingosine 1-phosphate receptor 4
S1PR5_HUMAN Q9H228 Sphingosine 1-phosphate receptor 5
SCTR_HUMAN P47872 Secretin receptor x
SSR1_HUMAN P30872 Somatostatin receptor type 1
SSR2_HUMAN P30874 Somatostatin receptor type 2
SSR3_HUMAN P32745 Somatostatin receptor type 3
SSR4_HUMAN P31391 Somatostatin receptor type 4
SSR5_HUMAN P35346 Somatostatin receptor type 5
SUCR1_HUMAN Q9BXA5 Succinate receptor 1
T2R31_HUMAN P59538 Taste receptor type 2 member 31
TA2R_HUMAN P21731 Thromboxane A2 receptor
TA2R1_HUMAN Q9NYW7 Taste receptor type 2 member 1 x
TAAR1_HUMAN Q96RJ0 Trace amine-associated receptor 1
TBB3_HUMAN Q13509 Tubulin beta-3 chain
TRFR_HUMAN P34981 Thyrotropin-releasing hormone receptor
TS1R1_HUMAN Q7RTX1 Taste receptor type 1 member 1 x
TS1R2_HUMAN Q8TE23 Taste receptor type 1 member 2 x
TS1R3_HUMAN Q7RTX0 Taste receptor type 1 member 3 x
TSHR_HUMAN P16473 Thyrotropin receptor
UR2R_HUMAN Q9UKP6 Urotensin-2 receptor
V1AR_HUMAN P37288 Vasopressin V1a receptor
V1BR_HUMAN P47901 Vasopressin V1b receptor
V2R_HUMAN P30518 Vasopressin V2 receptor
VIPR1_HUMAN P32241 Vasoactive intestinal polypeptide receptor 1
VIPR2_HUMAN P41587 Vasoactive intestinal polypeptide receptor 2
Total target proteins: 244 216

2017年5月公開